Larry David plays Nathan Flomm, who changes his identity to Rolly DaVore and moves to a small island off the coast of Massachusetts after giving up 10% of an electric car company that eventually is worth billions.
Jon Hamm plays Will Haney, Flomm's handsome rival and boss at the car company.
Kate Hudson plays Rhonda, Haney's wife who has a special friendship with Flomm.
Michael Keaton plays Joe Stumpo, the zany operator of the island's quarry.
Bill Hader plays Rags, Stumpo's henchman who agrees to help Rolly.
JB Smoove plays Jaspar, a local who blames Rolly for the end of his relationship.
Danny McBride plays Frank, an island local who befriends Rolly.
Eva Mendes plays Jennifer, an island resident who "takes an off-handed suggestion from Rolly a bit too seriously, causing Rolly no end of trouble."
Amy Ryan plays Wendy, Rolly's ex-girlfriend, who Rolly finds out has an adult secret.
Phillip Baker Hall plays McKenzie, the boss at a construction site who naively hires Rolly.