I'm all for people being called out if needed, but I think Andy got several things wrong and the whole thing came across as being envious of LCK's newfound fame. First of all, as far as I know, Louis has never said that HBO didn't let him make Lucky Louie how he wanted to make it. In fact, he's said that they allowed him to make the exact show he wanted to make. His disappointment, from what I know, came from HBO's unwillingness to give the show some rope and grow in a second season. Even then, though, Louis was always very grateful toward HBO, so I don't know where Andy got this idea.
The other item that baffles me is Andy taking issue with whether or not the reading glasses/masturbation story actually happened. Who cares? That line about if LCK can "swear to me in a court of law that's what happened" is so bizarre. Since when does comedy have to be something that actually happened? It's the idea that matters, not the reality of the situation, isn't it?
I love Andy Kindler but this whole thing just feels like an attention grab by unexpectedly going after the big fish. Maybe it's so rare that critically acclaimed (read: "good") projects also become among the most popular in any genre, Andy didn't know how to handle this. In any case, I'm sure there are many better targets out there than Louis.